Relpax 40 mg Tablet 3pcs

What Eletriptan is and what it is used for:

• 
  Eletriptan is one of a group of medicines called serotonin receptor agonists.
• Serotonin is a natural substance found in the brain that helps to narrow the blood vessels.
• Eletriptan can be used to treat migraine headache with or without aura in adults.
• Before the start of a migraine headache, you may experience a phase called an aura, which can involve vision disorders, numbness and speech disorders.

What you need to know before you use Eletriptan:

Do not use Eletriptan:

• If you are allergic (hypersensitive) to Eletriptan, or any of the other ingredients of this medicine
• If you have severe liver or kidney disease.
• If you have moderate to severe high blood pressure or untreated mild high blood pressure.
• If you have ever had heart problems, [e.g.
• Heart attack, angina, heart failure or significant abnormal heart rhythm (arrhythmia), temporary, sudden narrowing of one of the coronary arteries].
• If you have poor circulation (peripheral vascular disease).
• If you have ever had a stroke (even a mild one that lasted for only a few minutes or hours).
• If you have taken ergotamine or medicines like ergotamine (including methysergide) within 24 hours before or after taking Eletriptan.
• If you are taking any other medicines that end in ‘triptan’ (for example sumatriptan, rizatriptan, naratriptan, zolmitriptan, almotriptan and frovatriptan).

Warnings and precautions:

Talk to your doctor or pharmacist before taking Eletriptan if:

• You have diabetes.
• You smoke or use nicotine replacement therapy.
• You are male and over 40 years.
• You are female and post-menopausal.
• You or anybody in your family have coronary artery disease.
• You have ever been told that you may have an increased risk of heart disease, discuss this with your doctor before using Eletriptan.
• Repeat use of migraine medicines
• If you repeatedly use Eletriptan or any medicines for the treatment of migraine over several days or weeks, this can cause daily long-term headaches.
• Tell your doctor if you experience this as you might need to stop treatment for a while.

Other medicines and Eletriptan:

• Tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines.
• Taking Eletriptan together with some medicines may cause serious side effects.

Do not use Eletriptan if:

• You have taken ergotamine or medicines like ergotamine (including methysergide) within 24 hours before or after taking Eletriptan.
• You are taking any other medicines that end in ‘triptan’ (for example sumatriptan, rizatriptan, naratriptan, zolmitriptan, almotriptan and frovatriptan).

• Some medicines can affect the way Eletriptan works, or Eletriptan itself can reduce the effectiveness of other medicines taken at the same time.

These include:

• Drugs used to treat fungal infections (e.g.Ketoconazole and itraconazole).
• Drugs used to treat bacterial infections (e.g.Erythromycin, clarithromycin and josamycin).
• Drugs used to treat AIDS and HIV (e.g.Ritonavir, indinavir and nelfinavir).
• The herbal preparation St John’s wort (Hypericum perforatum) should not be taken at the same time as this medicine.
• If you already take St John’s wort, consult your doctor before stopping the St John’s wort preparation.
• Tell your doctor before starting treatment with Eletriptan, if you are taking some medicines (commonly referred to as ssris* or snris**), for depression and other mental disorders.
• These medicines may increase the risk of developing serotonin syndrome during combined use with certain migraine medications (review section 4.Possible side effects).

*ssris- Selective serotonin re-uptake inhibitors

**snris Serotonin norepinephrine re-uptake inhibitors

How to use Eletriptan:

• Always take this medicine exactly as your doctor has told you.
• Check with your doctor or pharmacist if you are not sure.

Adults:

• Your medicine can be taken at any time after the start of the migraine headache, but it is best to take it as soon as possible.
• However you should only take Eletriptan during the headache phase of the migraine.
• You should not take this medicine to prevent a migraine attack.
• The usual starting dose is one 40 mg tablet.
• Swallow each tablet whole with a drink of water.
• If the first tablet does not relieve your migraine, do not take a second tablet for the same attack.
• If after a first tablet your migraine is relieved and then comes back, you may take a second tablet.
• However, after taking the first tablet you must wait at least 2 hours before taking the second tablet.
• You should not take more than 80 mg (2 x 40 mg tablets) within 24 hours.
• If you find that a dose of one 40 mg tablet does not relieve your migraines, tell your doctor he or she may decide to increase the dose to two 40 mg tablets for future attacks.

Use in children and adolescents under 18 years:

• Eletriptan tablets are not recommended for children and adolescents under 18 years of age.

Elderly:

• Eletriptan tablets are not recommended for patients over 65 years of age.

Kidney Impairment:

• This medicine can be used in patients with mild or moderate kidney problems.
• In these patients a starting dose of 20 mg is recommended, and the total daily dose should not be more than 40 mg.
• Your doctor will tell you what dose to take.

• Liver Impairment
• This medicine can be used in patients with mild or moderate liver problems.
• No dose adjustment is required for mild or moderate liver impairment.

Possible side effects:

• Stop using the product and seek immediate medical attention if
  you develop urticaria, rash, tightness of the chest, wheezing, hypotension
• Tell your doctor immediately if you experience any of the following symptoms after taking this medicine.
• Chest pain and tightness, which may be intense and involve the throat.
• These may be symptoms of problems of the blood circulation of the heart (Ischaemic heart disease).
• Signs and symptoms of serotonin syndrome which may include restlessness, hallucinations, loss of co-ordination, fast heart beat, increase body temperature, fast changes in blood pressure and overactive reflexes.

How to store Eletriptan:

• Keep this medicine out of the sight and reach of children.
• Do not use this medicine after the expiry date which is stated on the pack or bottle.
• The expiry date refers to the last day of that month.
• There are no special storage instructions.
• Keep the tablets in their original container.
• Keep the container tightly closed when not in use to protect from moisture.