Profinal Xp 400 Mg 20 Tab

Ibuprofen / Caffeine 400 mg, 65 mg tablets


What Ibuprofen / Caffeine is and what it is used for:



The combination Ibuprofen / Caffeine is used for the symptomatic treatment of mild to moderate pain including headache, migraine, toothache, muscle pain, back pain, joint pain and menstrual pain.


Do not take Ibuprofen / Caffeine:



If you’re allergic to Ibuprofen or any other component of this medicine.

If you’ve had allergic reactions to Acetylsalicylic acid or other anti-inflammatory painkillers.

If you previously suffered from gastrointestinal bleeding following the use of non-steroidal anti- inflammatory drugs.

If you are suffering from an ulcer or bleeding in the stomach or small intestines or had at least two episodes in the past.

If you suffer from severe liver, kidney or heart problems.

If you are severely dehydrated.

If you have any active bleeding.

If you have conditions that increase the risk of bleeding.

If you are in the last 3 months of pregnancy.


Warnings and precautions:


Talk to your doctor about all your medical conditions before taking this medicine including:



If you have chronic inflammatory gastrointestinal diseases such as ulcerative colitis, Crohn’s disease, or others.

If you have systemic lupus erythematosus (SLE).

If you have problems with your blood cells.

If you have blood clotting problems.

If you have a high blood pressure or heart problems.

If you have liver or kidney problems.

If you have asthma or other conditions where it is difficult to breathe.

Ibuprofen and other similar medicines may cause ulcers, perforation and bleeding in the stomach or intestines. These can be serious.

Ibuprofen and other similar medicines are associated with a small increased risk of heart attacks and stroke, particularly when used in high doses for a long period of time.


Possible side effects


Stop using this product and seek immediate medical help if you develop rash; hives; itching; red, swollen, blistered, or peeling skin; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.


Serious side effects:



Gastrointestinal bleeding and ulcers

Kidney problems

Severe skin reactions


Other medicines and Ibuprofen / Caffeine


Tell your doctor about all the medicines you are taking.


Ibuprofen interacts with a lot of medicines including:



Other NSAIDs.

Anticoagulants and anti-platelets.

Diuretics.

Lithium.

Digoxin.

Steroids.

Methotrexate.

Immunosuppressant medications.

Some antibiotics.

Medicines used for depression.

Sulfonylureas.

Fluconazole and Voriconazole.

Some anti-viral medications.

Gingko biloba (herbal product).


How to take Ibuprofen / Caffeine:



This medicine is for adults and adolescents (12 years and older).

Take as indicated by your doctor.

Take with or right after a meal.

The usual recommended dose is one tablet 3 times a day.


How to store Ibuprofen / Caffeine:



Store at room temperature 68 to 77°F (20 to 25°C).

Keep this medicine out of reach of children.

Do not use this medicine after the expiry date stated on the package.

The expiry date refers to the last day of that month.